Next Gen Genetics

“In 6 months, we made a drug from scratch – personalised to baby KJ”

A newborn. A lethal mutation. A clock running out.

Kiran Musunuru, a cardiologist and geneticist, was one of the 2 lead doctors who created a custom CRISPR cure for a baby facing a fatal liver disease. A world first.

With no precedent and no time to lose, they sequenced all three billion letters of his genome, located the single genetic misspelling behind his disease, programmed CRISPR like a GPS – and delivered the edit using billions of microscopic “soap bubbles.” The result: a normally functioning organ. No transplant. A thriving child.

A life saved with personalised medication.

In this landmark conversation with Shoma Chaudhury, Founder-Director of Lucid Lines and Founder of SYNAPSE, watch him explain how they built a personalized gene editing cure from scratch in six months, whether we can scale such therapies for millions. And how we’re entering a “CRISPR generation”.